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Crystallographic Tools

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SUPERFLIP Adapting the Charge Flipping algorithm to biological macromolecule diffraction data:
  • ab initio determination of protein crystal structures at atomic resolution
  • heavy atom or anomalous scatterers substructure determination

* Dumas C and van der Lee A, Acta Cryst, D64 864-73 (2008)

* Palatinus L and Chapuis G, J Appl Cryst, 40, 786-790 (2007)

ACI-IMPBio
SelenoCYS Protocol for the incorporation of selenomethionine and selenocysteine into recombinant proteins overexpressed in Escherichia coli based on the use of a suitable cysteine auxotrophic strain Strub MP et al, Structure, 11, 1359-1367 (2003)
easYPipe Pipeline that contributes to the automation of ligand and fragment X-Ray crystallographic screening in structure-based drug design projects. Download of processed data from synchrotron, choice of best data for each dataset, determination of protein-ligand structures using Phenix, easy-to-use grouping of results. Muriel Gelin

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Centre de Biochimie Structurale
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