Structure evaluation based on hierarchical statistical potentials
EvDTree calculates structure-dependant substitution scores for the input protein structure using statistical potentials obtained from optimized decision trees. For each amino acid found the input protein, each possible mutation is evaluated by a statistical score that depends on the native amino acid type and on the 3D structural environment observed in the input structure.
If the input protein sequences are not aligned, they will be aligned using CLUSTALW. If only one PDB identifier or PDB structure chain is provided as input, the protein sequence will be self-evaluated against its own 3D structure.
Type your input query in the box below:
(Each sequence from the input text area is evaluated relatively to either the first structure chain found in the PDB file provided in the upload field or, by default, relatively to the first protein from the text area below whose name is a PDB chain identifier (eg., 1reiA, 2rhe or 4cpa_))
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or upload your input query from a file :
or use previous input/output compatible with EVDTREE:
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You may select similar tools below if you want to launch them in parallel on the same input:
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